Neoantigens

Tumors generate hundreds of mutations.  These mutations can generate neoantigens – mutated versions of normal proteins that become recognizable by patients’ own T-cells. Such T-cells recovered from patients can be used as a source of tumor T-cell therapies…

Vile, EC  (2016) Socializing Individualized T-Cell Cancer Immunotherapy. Molecular Therapy vol. 24 no. 7 1170-1173